The E-Institute of Chinese Internal Medicine

Release time:2015-01-09visits:(15)

The SHUTCM E-Institute of Chinese Internal Medicine is an academic research institution affiliated to the Shanghai Education Commission. The Institute aims to establish a novel pattern in creating an academic team, training the junior science talents and enhancing multidisciplinary development. Directorate

Prof. Liu Ping, a distinguished scientist in Hepatology, is the Chief researcher of the Institute.The Center has an expert team of ten well-known scholars from both home and abroad. Through a shared platform built by these scholars, extensive academic and research cooperation have been developed. In the past four years, we’ve published 78 scientific papers. These papers were indexed by Science Citation Index (SCI), with a total SCI IF (impact factor) of 242.675.

Our research interests

lChinese internal medicine

lHepatology

lMetabonomics & Proteomics

lCancer

lRheumatoid arthritis

Our representative Papers:

[1]Li H, Jia W. Cometabolism of microbes and host: implications for drug metabolism and drug-induced toxicity [J].Clin Pharmacol Ther, 2013, 94(5):574-581.(SCI IF 6.846)

[2]Zheng X., Xie G., Jia W. Metabolomic profiling in colorectal cancer: opportunities for personalized medicine[J]. Personalized Medicine, 2013, 10(7):741-755.(SCI IF 1.51)

[3]Song H. Y., Zhang L., Pan J. L., Yang L. L., Ji G. Bioactivity of five components of Chinese herbal formula Jiangzhi granules against hepatocellular steatosis[J]. J Integr Med, 2013, 11(4):262-268. (SCI IF 1.059)

[4]Liu T., Yang L. L., Zou L., Li D. F., Wen H. Z., Zheng P. Y., Xing L. J., Song H. Y., Tang X. D., Ji G. Chinese medicine formula lingguizhugan decoction improves Beta-oxidation and metabolism of Fatty Acid in high-fat-diet-induced rat model of Fatty liver disease[J]. Evid Based Complement Alternat Med, 2013, 2013:429738. (SCI IF 1.722)

[5]Wang M., Sun S., Wu T., Zhang L., Song H., Hao W., Zheng P., Xing L., Ji G. Inhibition of LXRalpha/SREBP-1c-Mediated Hepatic Steatosis by Jiang-Zhi Granule[J]. Evid Based Complement Alternat Med, 2013, 2013:584634. (SCI IF 1.722)

[6]Pan J., Wang M., Song H., Wang L., Ji G. The efficacy and safety of traditional Chinese medicine (jiang zhi granule) for nonalcoholic Fatty liver: a multicenter, randomized, placebo-controlled study [J]. Evid Based Complement Alternat Med, 2013, 2013:965723. (SCI IF 1.722)

[7]Liu Y., Zhang L., Song H., Ji G. Update on berberine in nonalcoholic Fatty liver disease[J]. Evid Based Complement Alternat Med, 2013, 2013:308134. (SCI IF 1.722)

[8]Sun S., Wang M., Song H., Wu T., Wei H., He S., Ding Z., Ji G. SCAP gene polymorphisms decrease the risk of nonalcoholic fatty liver disease infemales with metabolic syndrome[J]. J Genet, 2013, 92(3):565-570. (SCI IF 0.876)

[9]Sun Shanshan, Wang Miao, Song Haiyan, Hao Weiwei, Ji Guang. Berberine Ameliorates Ethanol-Induced Disruption of Intestinal Epithelial Tight Junction[J]. Global Journal of Gastroenterology & Hepatology, 2013, 1(1):58-65. (SCI IF 1.059)

[10]Gou X., Tao Q., Feng Q., Peng J., Sun S., Cao H., Zheng N., Zhang Y., Hu Y., Liu P. Urinary metabonomics characterization of liver fibrosis induced by CCl(4) in rats and intervention effects of Xia Yu Xue Decoction[J]. J Pharm Biomed Anal, 2013, 74:62-65. (SCI IF 2.947)

[11]Zhao Yu, Gou Xiao-Jun, Dai Jian-Ye, Peng Jing-Hua, Feng Qin, Sun Shu-Jun, Cao Hui-Juan, Zheng Ning-Ning, Fang Jun-Wei, Jiang Jian, Su Shi-Bing, Liu Ping, Hu Yi-Yang, Zhang Yong-Yu. Differences in Metabolites of Different Tongue Coatings in Patients with Chronic Hepatitis B [J]. Evidence-Based Complementary and Alternative Medicine, 2013, Article ID 204908, 12 pages, 2013. doi:10.1155/2013/204908. (SCI IF 1.722)

[12]Gou X., Tao Q., Feng Q., Peng J., Zhao Y., Dai J., Wang W., Zhang Y., Hu Y., Liu P. Urine metabolic profile changes of CCl4-liver fibrosis in rats and intervention effects of Yi Guan Jian Decoction using metabonomic approach[J]. BMC Complement Altern Med, 2013, 13:123. (SCI IF 2.082)

[13]Zhao Y., Gou X. J., Dai J. Y., Peng J. H., Feng Q., Sun S. J., Cao H. J., Zheng N. N., Fang J. W., Jiang J., Su S. B., Liu P., Hu Y. Y., Zhang Y. Y. Differences in metabolites of different tongue coatings in patients with chronichepatitis B[J]. Evid Based Complement Alternat Med, 2013, 2013:204908. (SCI IF 1.722)

[14]Gou X., Tao Q., Feng Q., Peng J., Zhao Y., Dai J., Wang W., Zhang Y., Hu Y., Liu P. Urine metabolic profile changes of CCl4-liver fibrosis in rats and intervention effects of Yi Guan Jian Decoction using metabonomic approach[J]. BMC Complement Altern Med, 2013, 13:123. (SCI IF 2.082)

[15]Yin X., Peng J., Zhao L., Yu Y., Zhang X., Liu P., Feng Q., Hu Y., Pang X. Structural changes of gut microbiota in a rat non-alcoholic fatty liver disease model treated with a Chinese herbal formula[J]. Syst Appl Microbiol, 2013, 36(3):188-196. (SCI IF 3.288)

[16]Peng J. H., Cui T., Huang F., Chen L., Zhao Y., Xu L., Xu L. L., Feng Q., Hu Y. Y. Puerarin ameliorates experimental alcoholic liver injury by inhibition of endotoxin gut leakage, Kupffer cell activation, and endotoxin receptors expression[J]. J Pharmacol Exp Ther, 2013, 344(3):646-654. (SCI IF 3.891)

[17]Meng S., Cao J., Feng Q., Peng J., Hu Y. Roles of chlorogenic Acid on regulating glucose and lipids metabolism: a review[J]. Evid Based Complement Alternat Med, 2013, 2013:801457. (SCI IF 1.722)

[18]Peng J., Li X., Feng Q., Chen L., Xu L., Hu Y. Anti-fibrotic effect of Cordyceps sinensis polysaccharide: Inhibiting HSC activation, TGF-beta1/Smad signalling, MMPs and TIMPs[J]. Exp Biol Med (Maywood), 2013, 238(6):668-677. (SCI IF 2.803)

[19]Gou X., Tao Q., Feng Q., Peng J., Sun S., Cao H., Zheng N., Zhang Y., Hu Y., Liu P. Urinary metabonomics characterization of liver fibrosis induced by CCl(4) in rats and intervention effects of Xia Yu Xue Decoction[J]. J Pharm Biomed Anal, 2013, 74:62-65. (SCI IF 2.947)

[20]Liang F., Li L., Wang M., Niu X., Zhan J., He X., Yu C., Jiang M., Lu A. Molecular network and chemical fragment-based characteristics of medicinal herbswith cold and hot properties from Chinese medicine[J]. J Ethnopharmacol, 2013, 148(3):770-779. (SCI IF 2.755)

[21]Liu B., Zhang H., Li J., Lu C., Chen G., Zhang G., Lu A., He X. Triptolide down-regulates Treg cells and the level of IL-10, TGF-beta, and VEGF in melanoma-bearing mice [J]. Planta Med, 2013, 79(15):1401-1407. (SCI IF 2.348)

[22]Wang M., Chen G., Lu C., Xiao C., Li L., Niu X., He X., Jiang M., Lu A. Rheumatoid arthritis with deficiency pattern in traditional Chinese medicine shows correlation with cold and hot patterns in gene expression profiles[J]. Evid Based Complement Alternat Med, 2013, 2013:248650. (SCI IF 1.722)

[23]Tao Y., Fang L., Yang Y., Jiang H., Yang H., Zhang H., Zhou H. Quantitative proteomic analysis reveals the neuroprotective effects of huperzineA for amyloid beta treated neuroblastoma N2a cells[J]. Proteomics, 2013, 13(8):1314-1324. (SCI IF 4.132)

[24]Hong S., Noh H., Chen H., Padia R., Pan Z. K., Su S. B., Jing Q., Ding H. F., Huang S. Signaling by p38 MAPK Stimulates Nuclear Localization of the Microprocessor Component p68 for Processing of Selected Primary MicroRNAs[J]. Sci Signal, 2013, 6(266):a16. (SCI IF 7.648)

[25]Noh H., Hong S., Huang S. Role of urokinase receptor in tumor progression and development [J]. Theranostics, 2013, 3(7):487-495. (SCI IF 7.806)

[26]Shao J., Teng Y., Padia R., Hong S., Noh H., Xie X., Mumm J. S., Dong Z., Ding H. F., Cowell J., Kim J., Han J., Huang S. COP1 and GSK3beta cooperate to promote c-Jun degradation and inhibit breast cancer cell tumorigenesis[J]. Neoplasia, 2013, 15(9):1075-1085. (SCI IF 5.47)

[27]Liu T., Yang L. L., Zou L., Li D. F., Wen H. Z., Zheng P. Y., Xing L. J., Song H. Y., Tang X. D., Ji G. Chinese medicine formula lingguizhugan decoction improves Beta-oxidation and metabolism of Fatty Acid in high-fat-diet-induced rat model of Fatty liver disease[J]. Evid Based Complement Alternat Med, 2013, 2013:429738. (SCI IF 1.722)

[28]Tao Y. Y., Wang Q. L., Shen L., Fu W. W., Liu C. H. Salvianolic acid B inhibits hepatic stellate cell activation through transforming growth factor beta-1 signal transduction pathway in vivo and in vitro[J]. Exp Biol Med (Maywood), 2013, 238(11):1284-1296. (SCI IF 2.803)

[29]Yang T., Shen D. P., Wang Q. L., Tao Y. Y., Liu C. H. Investigation of the absorbed and metabolized components of Danshen from Fuzheng Huayu recipe and study on the anti-hepatic fibrosis effects of these components [J]. J Ethnopharmacol, 2013, 148(2):691-700. (SCI IF 2.755)

[30]Yin X., Peng J., Zhao L., Yu Y., Zhang X., Liu P., Feng Q., Hu Y., Pang X. Structural changes of gut microbiota in a rat non-alcoholic fatty liver disease model treated with a Chinese herbal formula[J]. Syst Appl Microbiol, 2013, 36(3):188-196. (SCI IF 3.288)

[31]Gou X., Tao Q., Feng Q., Peng J., Sun S., Cao H., Zheng N., Zhang Y., Hu Y., Liu P. Urinary metabonomics characterization of liver fibrosis induced by CCl(4) in rats and intervention effects of Xia Yu Xue Decoction[J]. J Pharm Biomed Anal, 2013, 74:62-65. (SCI IF 2.947)

[32]Gou X., Tao Q., Feng Q., Peng J., Zhao Y., Dai J., Wang W., Zhang Y., Hu Y., Liu P. Urine metabolic profile changes of CCl4-liver fibrosis in rats and intervention effects of Yi Guan Jian Decoction using metabonomic approach[J]. BMC Complement Altern Med, 2013, 13:123. (SCI IF 2.082)

[33]Sun M., Cao H., Sun L., Dong S., Bian Y., Han J., Zhang L., Ren S., Hu Y., Liu C., Xu L., Liu P. Antitumor activities of kushen: literature review [J]. Evid Based Complement Alternat Med, 2012, 2012:373219. (SCI IF 4.774)

[34]Zhang H., Lv H., Huang P. X., Lin Y., Hu X. C., Liu P. Comparative Study of TCM Syndrome Scale for Liver Disease and Chronic Liver Disease Questionnaire Based on Assessment of Posthepatitic Cirrhosis[J]. Evid Based Complement Alternat Med, 2012, 2012:496575. (SCI IF 4.774)

[35]Wang X. L., Jia D. W., Liu H. Y., Yan X. F., Ye T. J., Hu X. D., Li B. Q., Chen Y. L., Liu P. Effect of Yiguanjian decoction on cell differentiation and proliferation in CCl(4)-treated mice[J]. World J Gastroenterol, 2012, 18(25):3235-3249. (SCI IF 2.471)

[36]Liu P. Fuzheng huayu capsule in the treatment of liver fibrosis: clinical evidence and mechanism of action [J]. Chin J Integr Med, 2012, 18(5):398-400. (SCI IF 0.799)

[37]Du JX, Sun M. Y., Du GL, Li F. H., Liu C., Mu Y. P., Chen G. F., Long A. H., Bian Y. Q., Liu J., Liu C. H., Hu Y. Y., Xu L. M., Liu P. Ingredients of Huangqi decoction slow biliary fibrosis progression by inhibitingthe activation of the transforming growth factor-beta signaling pathway[J]. BMC Complement Altern Med, 2012, 12(1):33. (SCI IF 2.241)

[38]Zhang H., Li Q. Y., Guo Z. Z., Guan Y., Du J, Lu Y. Y., Hu Y. Y., Liu P., Huang S., Su S. B. Serum levels of microRNAs can specifically predict liver injury of chronic hepatitis B[J]. World J Gastroenterol, 2012, 18(37):5188-5196. (SCI IF 2.471)

[39]Wang X., Wang X., Xie G., Zhou M., Yu H., Lin Y., Du G, Luo G., Jia W., Liu P. Urinary Metabolite Variation is Associated with Pathological Progression of the Post-Hepatitis B Cirrhosis Patients[J]. J Proteome Res, 2012, 11(7):3838-3847. (SCI IF 5.113)

[40]Jiang M., Zhang C., Zheng G., Guo H., Li L., Yang J., Lu C., Jia W., Lu A. Traditional Chinese medicine zheng in the era of evidence-based medicine: a literature analysis[J]. Evid Based Complement Alternat Med, 2012, 2012:409568. (SCI IF 4.774)

[41]Lv J., Zhao Z., Chen Y., Wang Q., Tao Y., Yang L., Fan T. P., Liu C. The Chinese herbal decoction danggui buxue tang inhibits angiogenesis in a rat model of liver fibrosis [J]. Evid Based Complement Alternat Med, 2012, 2012:284963. (SCI IF 4.774)

[42]Li S., Wang L., Yan X., Wang Q., Tao Y., Li J., Peng Y., Liu P., Liu C. Salvianolic Acid B Attenuates Rat Hepatic Fibrosis via Down-regulating Angiotensin II Signaling[J]. Evid Based Complement Alternat Med, 2012, 2012:160726. (SCI IF 4.774)

[43]Xing F., Tan Y., Yan G. J., Zhang J. J., Shi Z. H., Tan S. Z., Feng N. P., Liu C. H. Effects of Chinese herbal cataplasm Xiaozhang Tie on cirrhotic ascites[J]. J Ethnopharmacol, 2012, 139(2):343-349. (SCI IF 3.014)

[44]Guo Z., Yu S., Guan Y., Li Y. Y., Lu Y. Y., Zhang H., Su S. B. Molecular Mechanisms of Same TCM Syndrome for Different Diseases and Different TCM Syndrome for Same Disease in Chronic Hepatitis B and Liver Cirrhosis[J]. Evid Based Complement Alternat Med, 2012, 2012:120350. (SCI IF 4.774)

[45]Song Y. N., Zhang H., Guan Y., Peng J. H., Lu Y. Y., Hu Y. Y., Su S. B. Classification of Traditional Chinese Medicine Syndromes in Patients with Chronic Hepatitis B by SELDI-Based ProteinChip Analysis[J]. Evid Based Complement Alternat Med, 2012, 2012:626320. (SCI IF 4.774)

[46]Li Q. Y., Guo Z. Z., Liang J., Zhang W., Xu L. M., Gao Y. Q., Wang X. S., Xue D. Y., Su S. B. Interleukin-10 genotype correlated to deficiency syndrome in hepatitis B cirrhosis[J]. Evid Based Complement Alternat Med, 2012, 2012:298925. (SCI IF 4.774)

[47]Yu S., Guo Z., Guan Y., Lu Y. Y., Hao P., Li Y., Su S. B. Combining ZHENG Theory and High-Throughput Expression Data to Predict New Effects of Chinese Herbal Formulae[J]. Evid Based Complement Alternat Med, 2012, 2012:986427. (SCI IF 4.774)

[48]Zhang H., Li Q. Y., Guo Z. Z., Guan Y., Du J, Lu Y. Y., Hu Y. Y., Liu P., Huang S., Su S. B. Serum levels of microRNAs can specifically predict liver injury of chronic hepatitis B[J]. World J Gastroenterol, 2012, 18(37):5188-5196. (SCI IF 2.471)

[49]Peng J. H., Cui T., Sun Z. L., Huang F., Chen L., Xu L., Feng Q., Hu Y. Y. Effects of Puerariae Radix Extract on Endotoxin Receptors and TNF-alpha Expression Induced by Gut-Derived Endotoxin in Chronic Alcoholic Liver Injury[J]. Evid Based Complement Alternat Med, 2012, 2012:234987. (SCI IF 4.774)

[50]Peng J., Cui T., Huang F., Chen L., Zhao Y., Xu L., Xu L., Feng Q., Hu Y. Puerarin Ameliorates Experimental Alcoholic Liver Injury by Inhibition of Endotoxin Gut-leakage, kupffer Cell Activation and Lipopolysaccharide Receptors Expression[J]. J Pharmacol Exp Ther, 2012. (SCI IF 3.828)

[51]Wu T., Yang M., Wei H. F., He S. H., Wang S. C., Ji G. Application of metabolomics in traditional Chinese medicine differentiation of deficiency and excess syndromes in patients with diabetes mellitus[J]. Evid Based Complement Alternat Med, 2012, 2012:968083. (SCI IF 4.774)

[52]Fan S., Zhang Y., Hu N., Sun Q., Ding X., Li G., Zheng B., Gu M., Huang F., Sun Y. Q., Zhou Z., Lu X., Huang C., Ji G. Extract of Kuding Tea Prevents High-Fat Diet-Induced Metabolic Disorders in C57BL/6 Mice via Liver X Receptor (LXR) beta Antagonism[J]. PLoS One, 2012, 7(12):e51007. (SCI IF 4.092)

[53]Wu T., Song H. Y., Ji G. Abnormal bone metabolism in Crohn's disease [J]. Front Biosci, 2012, 17:2675-2683. (SCI IF 3.52)

[54]Zhou M., Wang S., Zhao A., Wang K., Fan Z., Yang H., Liao W., Bao S., Zhao L., Zhang Y., Yang Y., Qiu Y., Xie G., Li H., Jia W. Transcriptomic and metabonomic profiling reveal synergistic effects of quercetinand resveratrol supplementation in high fat diet fed mice[J]. J Proteome Res, 2012, 11(10):4961-4971. (SCI IF 5.113)

[55]Liao W., Wei H., Wang X., Qiu Y., Gou X., Zhang X., Zhou M., Wu J., Wu T., Kou F., Zhang Y., Bian Z., Xie G., Jia W. Metabonomic Variations Associated with AOM-induced Precancerous Colorectal Lesions and Resveratrol Treatment[J]. J Proteome Res, 2012, 11(6):3436-3448. (SCI IF 5.113)

[56]Chen Yue-Lei, Lv Jing, Ye Xiao-Lei, Sun Ming-Yu, Xu Qin, Liu Cheng-Hai, Min Li-Hua, Li Hui-Ping, Liu Ping, Ding Xiaoyan. Sorafenib inhibits transforming growth factor β1-Mediated Epithelial-Mesenchymal Transition and apoptosis in mouse hepatocytes [J]. Hepatology, 2011, 53(5):1708-1718. (SCI IF 11.665)

[57]Fu W. W., Fu J. N., Zhang W. M., Sun L. X., Pei Y. H., Liu P. Platycoside O, a new triterpenoid saponin from the roots of Platycodon grandiflorum[J]. Molecules, 2011, 16(6):4371-4378.(SCI IF 1.988)

[58]Fu Wen-Wei, Tan Chang-Heng, Zhuang Peng-Yu, Yang Shu-Min, Luo Hong-Feng, Tan Jun-Jie, Liu Ping, Zhu Da-Yuan. Purinium Derivatives with Antitumor Activities from Heterostemma alatum Wight [J]. Heterocycles, 2011, 6(83):1405-1408. (SCI IF 1.093)

[59]Li J., Lu Y., Xiao C., Lu C., Niu X., He X., Zhao H., Tan Y., Lu A. Comparison of toxic reaction of Tripterygium wilfordii multiglycoside in normal and adjuvant arthritic rats[J]. J Ethnopharmacol, 2011. (SCI IF 2.466)

[60]Ma W., Bai W., Lin C., Zhou P., Xia L., Zhao C., Hao Y., Ma H., Liu X., Wang J., Yuan H., Xie Y., Lu A. Effects of Sanyinjiao (SP6) with electroacupuncture on labor pain in women during labor[J]. Complement Ther Med, 2011, 19 Suppl 1:S13-S18. (SCI IF 1.484)

[61]Zhang C., Jiang M., Lu A. P. Evidence-based Chinese medicine for rheumatoid arthritis[J]. J Tradit Chin Med, 2011, 31(2):152-157. (SCI IF 0.296)

[62]Zhang C., Jiang M., Lu A. A traditional Chinese medicine versus Western combination therapy in the treatment of rheumatoid arthritis: two-stage study protocol for a randomized controlled trial [J]. Trials, 2011, 12:137. (SCI IF 2.08)

[63]Xing L. J., Zhang L., Liu T., Hua Y. Q., Zheng P. Y., Ji G. Berberine reducing insulin resistance by up-regulating IRS-2 mRNA expression in nonalcoholic fatty liver disease (NAFLD) rat liver[J]. Eur J Pharmacol, 2011, 668(3):467-471.(SCI IF 2.737)

[64]Hai-Yan Song, Zhi-Min Mao, Li-Li Yang, Tao Liu, Dong-Fei Li, Li Zhang, Ying-Li Ge, Pei-Yong Zheng, Ping Liu, Xiao-Qi Zhang, Guang Ji. Dangfei Liganning Capsules Attenuate the Susceptibility of Rat Nonalcoholilc Fatty Liver to Carbon Tetrachloride Toxicity[J]. Journal of Traditional Chinese Medicine, 2011, 31(4):256-262. (SCI IF 0.296)

[65]Xie Y. Q., Wang H., Wu Y. P., Yin D. H., Wang Z. S., Huang Y. H. Association of APOE polymorphisms and insulin resistance with TCM syndromes in type 2 diabetes patients with macroangiopathy[J]. Mol Med Rep, 2011, 4(6):1219-1223. (SCI IF 0.307)

[66]Zhang HuiZhou Qian-MeiLu Yi-YuDu JiaSu Shi-Bing. Aidi Injection Alters the Expression Profiles of MicroRNAs in Human Breast Cancer Cells [J]. Journal of Traditional Chinese Medicine, 2011, 31(1):10-16. (SCI IF 0.296)

[67]Zhou Q. M., Wang X. F., Liu X. J., Zhang H., Lu Y. Y., Huang S., Su S. B. Curcumin improves MMC-based chemotherapy by simultaneously sensitising cancer cells to MMC and reducing MMC-associated side-effects[J]. Eur J Cancer, 2011, 47(14):2240-2247. (SCI IF 4.944)

[68]Liu C., Tao Q., Sun M., Wu J. Z., Yang W., Jian P., Peng J., Hu Y., Liu C., Liu P. Kupffer cells are associated with apoptosis, inflammation and fibrotic effects in hepatic fibrosis in rats[J]. Lab Invest, 2010, 90(12):1805-1816. (SCI IF 4.405)

[69]Hu X. D., Jiang S. L., Liu C. H., Hu Y. Y., Liu C., Sun M. Y., Chen G. F., Liu P. Preventive effects of 1,25-(OH)2VD3 against ConA-induced mouse hepatitis through promoting vitamin D receptor gene expression[J]. Acta Pharmacol Sin, 2010, 31(6):703-708. (SCI IF 1.909)

[70]Li Xin, Yang Songbing, Qiu Yunping, Zhao Tie, Chen Tianlu, Su Mingming, Chu Lixi, Lv Aiping, Liu Ping, Jia Wei. Urinary metabolomics as a potentially novel diagnostic and stratification tool for knee osteoarthritis [J]. Metabolomics, 2010, 6(1):109-118. (SCI IF 3.608)

[71]Jiang M., Zhao J., Lu A., Zha Q., He Y. Does gastrointestinal adverse drug reaction influence therapeutic effect in the treatment of rheumatoid arthritis? [J]. J Altern Complement Med, 2010, 16(2):143-144. (SCI IF 1.498)

[72]Lu C., Xiao C., Chen G., Jiang M., Zha Q., Yan X., Kong W., Lu A. Cold and heat pattern of rheumatoid arthritis in traditional Chinese medicine: distinct molecular signatures identified by microarray expression profiles in CD4-positive T cell [J]. Rheumatol Int, 2010. (SCI IF 1.431)

[73]Zhao H., Luo Y., Lu C., Lin N., Xiao C., Guan S., Guo D. A., Liu Z., Ju D., He X., Lu A. Enteric mucosal immune response might trigger the immunomodulation activity of Ganoderma lucidum polysaccharide in mice[J]. Planta Med, 2010, 76(3):223-227. (SCI IF 2.369)

[74]Gao Xianfu, Zhao Aihua, Zhou Mingmei, Lin Jingchao, Qiu Yunping, Su Mingming, Jia Wei. GC/MS-based urinary metabolomics reveals systematic differences in metabolism and ethanol response between Sprague–Dawley and Wistar rats [J]. Metabolomics, 2010, 7(3):363-374. (SCI IF 3.608)

[75]Lu Y. L., He Y. Q., Wang M., Zhang L., Yang L., Wang Z. T., Ji G. Characterization of nuciferine metabolism by P450 enzymes and uridine diphosphate glucuronosyltransferases in liver microsomes from humans and animals[J]. Acta Pharmacol Sin, 2010, 31(12):1635-1642. (SCI IF 1.909)

[76]Yan X., Zhou T., Tao Y., Wang Q., Liu P., Liu C. Salvianolic acid B attenuates hepatocyte apoptosis by regulating mediators in death receptor and mitochondrial pathways.[J]. Exp Biol Med (Maywood), 2010, 235(5):623-632. (SCI IF 2.954)

[77]Wang Q. L., Tao Y. Y., Yuan J. L., Shen L., Liu C. H. Salvianolic acid B prevents epithelial-to-mesenchymal transition through the TGF-beta1 signal transduction pathway in vivo and in vitro.[J]. BMC Cell Biol, 2010, 11:31. (SCI IF 2.464)

[78]Wang Q. L., Yuan J. L., Tao Y. Y., Zhang Y., Liu P., Liu C. H. Fuzheng Huayu recipe and vitamin E reverse renal interstitial fibrosis through counteracting TGF-beta1-induced epithelial-to-mesenchymal transition. [J]. J Ethnopharmacol, 2010, 127(3):631-640. (SCI IF 2.466)

Our experts

Chief Researcher: Prof. Liu Ping, Shanghai University of Traditional Chinese Medicine

Specially-appointed Researchers

Prof. Lu Aiping, School of Chinese Medicine, Hong Kong Baptist University

Prof. Ling Changquan, Changhai Hospital, the Second Military Medical University

Prof. Liu Chenghai, Institute of Liver Disease, Shanghai University of Traditional Chinese Medicine

Prof. Ji Guang, Shanghai University of Traditional Chinese Medicine

Prof. Zhou Hu, Shanghai Institute of Materia Medica, Chinese Academy of Sciences

Prof. Huang Shang, Tenured Professor, Medical College of Georgia, Georgia Health Sciences University

Prof. Su Shibing, Shanghai University of Traditional Chinese Medicine

Prof. Jia Wei, Tenured Professor, Cancer Center, University of Hawaii

Prof. Tang Xudong, Xiyuan Hospital, China Academy of Chinese Medical Sciences

Prof. Hu Yiyang, Shuguang Hospital, Shanghai University of Traditional Chinese Medicine

Contacts Us:

Dr. Wang Xiaoning, Associate Professor

Address: Room 2329,Building 2, 1200 Cailun Road, Shanghai 201203, China

Tel: 021-51322444

Fax: 021-51322445

Email: carl95@163.com

http://e-neike.shutcm.edu.cn